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Article

Phosphorylation of serine 13 is required for the proper function of the Hsp90 co-chaperone, Cdc37.

The Journal of biological chemistry - 3 Oct 2003

Shao Jieya, Prince Thomas, Hartson Steven D, Matts Robert L

Abstract excerpt

The Hsp90 co-chaperone Cdc37 provides an essential function for the biogenesis and support of numerous protein kinases. In this report, we demonstrate that mammalian Cdc37 is phosphorylated on Ser13 in situ in rabbit reticulocyte lysate and in cultured K562 cells and that casein kinase II is capable of quantitatively phosphorylating recombinant Cdc37 at this site. Mutation of Ser13 to either Ala or Glu...

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Identifiers

PMID: 12930845
DOI: 10.1074/jbc.C300330200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Phosphorylation of serine 13 is required for the proper function of the Hsp90 co-chaperone, Cdc37.PMID 12930845Read ↗

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