Article
Exposure of protein kinase motifs that trigger binding of Hsp90 and Cdc37.
Biochemical and biophysical research communications - 23 Dec 2005
Prince Thomas, Matts Robert L
Abstract excerpt
Hsp90 and its co-chaperone Cdc37 are required for the activity of numerous eukaryotic protein kinases. c-Jun N-terminal kinases (JNKs) appear to be Hsp90-independent kinases, as their activity is unaffected by Hsp90 inhibition. It is currently unknown why some protein kinases are Hsp90- and Cdc37...
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