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Article

Immunophenotypic analysis of the T cell receptor V beta repertoire in CD4+ and CD8+ lymphocytes from normal peripheral blood.

Cytometry - 15 Jun 1996

McCoy J P, Overton W R, Schroeder K, Blumstein L, Donaldson M H

Abstract excerpt

The antigenic specificity of the majority of T lymphocytes in the peripheral blood is determined by the combination of alpha and beta variable region chains present in the T cell receptor complex. Currently, the V beta chains are grouped into 25 families. Historically, determination of V beta usage has relied on detection of gene rearrangement on the nucleic acid level; however, with the increased availability of...

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PMID: 8817091
DOI: 10.1002/(SICI)1097-0320(19960615)26:2<148::AID-CYTO8>3.0.CO;2-C

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Source receipt: pubmed, retrieved 7 Sept 2026.

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