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Article

Limited heterogeneity of T cell receptor BV usage in aplastic anemia

1 Sept 2001

Abstract excerpt

Immune mediation of aplastic anemia (AA) has been inferred from clinical responsiveness to immunosuppressive therapies and a large body of circumstantial laboratory evidence. However, neither the immune response nor the nature of the antigens recognized has been well characterized. We established a large number of CD4 and CD8 T cell clones from a patient with AA and analyzed their T cell receptor (TCR) usage....

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Identifiers

PMID: 11544283
DOI: 10.1172/jci12687

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