Article
CARD15/NOD2 single nucleotide polymorphisms do not confer susceptibility to type I psoriasis.
The British journal of dermatology - 1 Sept 2004
Plant D, Lear J, Marsland A, Worthington J, Griffiths C E M
Abstract excerpt
BACKGROUND: A psoriasis susceptibility locus on chromosome 16q was identified recently. This region coincides with a locus predisposing to Crohn's disease. Patients with Crohn's disease have a fivefold greater relative risk for development of psoriasis. In Crohn's disease mutation of the caspase recruitment domain family, member 15 (CARD15) gene (chromosome 16q12.1) confers susceptibility. In light of the overlap...
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