Article
Croatian population data for the C677T polymorphism in methylenetetrahydrofolate reductase: frequencies in healthy and atherosclerotic study groups.
Clinica chimica acta; international journal of clinical chemistry - 1 Sept 2003
Zuntar Irena, Topić Elizabeta, Vukosavić Duro, Vuković Vlasta, Demarin Vida, Begonja Antonija, Antoljak Natasa, Simundić Ana Maria
Abstract excerpt
BACKGROUND: The aim of this study was to investigate the frequency of C677T methylenetetrahydrofolate reductase (MTHFR) mutation in healthy Croatian volunteers and in patients with atherosclerosis. METHODS: The C677T MTHFR gene mutation was determined by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) in 640 subjects, residents of the Zagreb city or Zagreb surroundings. Control group...
Topics
- Adult
- Aged
- Arteriosclerosis
- Croatia
- Female
- Gene Frequency
- Genetics, Population
- Genotype
- Humans
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)