Article
Methylenetetrahydrofolate reductase C677T and methionine synthase A2756G gene polymorphisms and associated risk of cardiovascular diseases: A study from Jammu region.
Indian heart journal - 1 Jan 2000
Raina Jyotdeep K, Sharma Minakashee, Panjaliya Rakesh K, Bhagat Minakshi, Sharma Ravi, Bakaya Ashok, Kumar Parvinder
Abstract excerpt
AIM: Potent risk factors at both genetic and non-genetic levels are accountable for susceptibility and instigation of different cardiovascular phenotypes. Recently, homocysteine is being identified as an important predictor for cardiovascular diseases. Homocysteine remethylation plays a key role in the synthesis of methionine and S-adenosine methionine. Methylenetetrahydrofolate reductase (MTHFR) and methionine...
Topics
- 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
- Adult
- Biomarkers
- Cardiovascular Diseases
- DNA
- Female
- Genotype
- Humans
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)
- Middle Aged
- Polymerase Chain Reaction
- Polymorphism, Genetic