Article
Association of methylenetetrahydrofolate reductase C677T and cystathionine β-synthase polymorphisms in cardiovascular disease in the algerian population.
Genetic testing and molecular biomarkers - 1 Dec 2010
Houcher Bakhouche, Houcher Zahira, Touabti Abderrezak, Begag Samia, Torun Didem, Eğin Yonca, Akar Nejat, Kadour Fatima
Abstract excerpt
AIM: Polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) and cystathionine β-synthase (CBS) genes, involved in the intracellular metabolism of homcysteine, can result in hyperhomocysteinemia. The objective of this study was to evaluate prevalence estimates of MTHFR C677T and the CBS insertion of 68-bp (844ins68) polymorphisms among individuals with cardiovascular disease (CVD). METHODS: In total, 131...
Topics
- Adult
- Aged
- Aged, 80 and over
- Algeria
- Cardiovascular Diseases
- Cystathionine beta-Synthase
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Humans
