Methylenetetrahydrofolate reductase C677T polymorphism is associated with increased risk of coronary artery disease in young South African Indians.

doi:10.1016/j.gene.2015.06.044

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Methylenetetrahydrofolate reductase C677T polymorphism is associated with increased risk of coronary artery disease in young South African Indians.

Gene - 15 Oct 2015

Ramkaran Prithiksha, Phulukdaree Alisa, Khan Sajidah, Moodley Devapregasan, Chuturgoon Anil A

Abstract excerpt

Methylenetetrahydrofolate reductase (MTHFR) reduces 5',10'-methylenetetrahydrofolate to 5'-methyltetrahydrofolate, and is involved in remethylation of homocysteine to methionine, two important reactions involved in folate metabolism and methylation pathways. The common MTHFR C677T single nucleotide polymorphism (SNP) (rs1801133) has been associated with raised levels of homocysteine, a well known risk factor for...

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PMID: 26095803
DOI: 10.1016/j.gene.2015.06.044

Genes

CAD
MTHFR

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Methylenetetrahydrofolate reductase C677T polymorphism is associated with increased risk of coronary artery disease in young South African Indians.PMID 26095803Read ↗

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