Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Spir2; a novel QTL on chromosome 4 contributes to susceptibility to pneumococcal infection in mice.

BMC genomics - 11 Apr 2013

Wisby Laura, Fernandes Vitor E, Neill Daniel R, Kadioglu Aras, Andrew Peter W, Denny Paul

Abstract excerpt

BACKGROUND: Streptococcus pneumoniae causes over one million deaths worldwide annually, despite recent developments in vaccine and antibiotic therapy. Host susceptibility to pneumococcal infection and disease is controlled by a combination of genetic and environmental influences, but current knowledge remains limited. RESULTS: In order to identify novel host genetic variants as predictive risk factors or as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacteremia
Share to Breeding
Share to Chromosomes, Mammalian

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Lod Score

Share to Microfilament Proteins

Share to Pneumococcal Infections

Share to Quantitative Trait Loci

Share to Streptococcus pneumoniae

Source

Open in PubMed Open full text

Identifiers

PMID: 23577770
DOI: 10.1186/1471-2164-14-242
PMCID: PMC3751763

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Spir2; a novel QTL on chromosome 4 contributes to susceptibility to pneumococcal infection in mice.PMID 23577770Read ↗

LacR and TrxB are key virulence factors involved in pneumococcal meningitis as identified by a genome-wide association studySemantic proximity Read ↗

Genetic Architecture of Group A Streptococcal Necrotizing Soft Tissue Infections in the Mouse.Semantic proximity Read ↗

An in vivo atlas of host-pathogen transcriptomes during Streptococcus pneumoniae colonization and disease.Semantic proximity Read ↗

Dissection of Host Susceptibility to Bacterial Infections and Its Toxins.Semantic proximity Read ↗

A major locus conferring susceptibility to infection by Streptococcus pneumoniae in mice.Semantic proximity Read ↗

Identification of candidate susceptibility and resistance genes of mice infected with Streptococcus suis type 2.Semantic proximity Read ↗

Characterization of the innate immune response to Streptococcus pneumoniae infection in zebrafishSemantic proximity Read ↗

Joint sequencing of human and pathogen genomes reveals the genetics of pneumococcal meningitisSemantic proximity Read ↗

A comprehensive analysis of pneumococcal two-component system regulatory networksSemantic proximity Read ↗

Identification of pneumococcal colonization determinants in the stringent response pathway facilitated by genomic diversity.Semantic proximity Read ↗

Susceptibility and resistance to pneumococcal disease in mice.Semantic proximity Read ↗

Susceptibility to Klebsiella pneumonaie infection in collaborative cross mice is a complex trait controlled by at least three loci acting at different time points.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.