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Article

The lipid phosphatase LPP3 regulates extra-embryonic vasculogenesis and axis patterning.

Development (Cambridge, England) - 1 Oct 2003

Escalante-Alcalde Diana, Hernandez Lidia, Le Stunff Hervé, Maeda Ryu, Lee Hyun-Shik, Jr-Gang-Cheng, Sciorra Vicki A, Daar Ira, Spiegel Sarah, Morris Andrew J, Stewart Colin L

Abstract excerpt

Bioactive phospholipids, which include sphingosine-1-phosphate, lysophosphatidic acid, ceramide and their derivatives regulate a wide variety of cellular functions in culture such as proliferation, apoptosis and differentiation. The availability of these lipids and their products is regulated by the lipid phosphate phosphatases (LPPs). Here we show that mouse embryos deficient for LPP3 fail to form a...

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PMID: 12925589
DOI: 10.1242/dev.00635

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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