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Article

Identification of target genes of the p16INK4A-pRB-E2F pathway.

The Journal of biological chemistry - 14 Nov 2003

Vernell Richard, Helin Kristian, Müller Heiko

Abstract excerpt

Deregulation of the retinoblastoma protein (pRB) pathway is a hallmark of human cancer. The core members of this pathway include the tumor suppressor protein, pRB, which through binding to a number of cellular proteins, most notably members of the E2F transcription factor family, regulates progression through the cell division cycle. With the aim of identifying transcriptional changes provoked by deregulation of...

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PMID: 12923195
DOI: 10.1074/jbc.M304930200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Identification of target genes of the p16INK4A-pRB-E2F pathway.PMID 12923195Read ↗

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