Article
[The phenotypic transformation of renal tubular epithelial cells affected by pathological stimuli].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences - 18 Feb 2003
Li Ling, Zou Wanzhong, Zhang Bo, Wang Shenglan, Guo Hua
Abstract excerpt
OBJECTIVE: To investigate the effects of low bovine serum, high glucose and high albumin on the phenotypic transformation of cultured renal tubular epithelial cells to mesenchymal cells. METHODS: The human kidney proximal tubular cells were cultured for 7 days in the presence of low bovine serum (0.2 mol.L-1), high glucose (4.5 g.L-1) and high albumin (15 g.L-1), and morphological changes were assessed by...
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