Article
[Phenotypic and functional alterations of mesangial cells in patients with diabetic nephropathy].
Zhonghua yi xue za zhi - 25 Nov 2001
Liu Z, Chen Z, Li Y
Abstract excerpt
OBJECTIVE: To explore the phenotypic and functional changes of glomerular mesangial cells (MC) in the development of diabetic nephropathy (DN). METHODS: Renal biopsy specimens were obtained from patients with type II DN. MC from microdissected glomeruli were cultured in vitro. Both the cells deriving from minute piece of renal biopsy specimen of type 2 DN with overt proteinuria and from transplanted donors'...
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