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Article

Renal lymph circulation blockage alters the epithelial cell phenotype and tubular integrity: role of distinct regulation of BMP7 and TGF-β/Smads signaling pathway.

International urology and nephrology - 1 Jun 2014

Liu Gang, Cheng Jing, Guan Guangju, Jia Zhanjun

Abstract excerpt

AIMS: To investigate the effect of lymph circulation blockage on the alteration of renal epithelial cell phenotype and the tubular integrity, as well as the underlying mechanisms. METHODS: Wistar rats received left renal lymph ligation and right renal nephrectomy (KL group) or right renal nephrectomy without lymph ligation (KN group) and then were killed on day 14, day 28 and day 56. The urine, blood and kidney...

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Identifiers

PMID: 24633697
DOI: 10.1007/s11255-014-0652-y

Genes

BMP7

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