Article
Evaluation of 3'-azido-3'-deoxythymidine, morphine, and codeine as probe substrates for UDP-glucuronosyltransferase 2B7 (UGT2B7) in human liver microsomes: specificity and influence of the UGT2B7*2 polymorphism.
Drug metabolism and disposition: the biological fate of chemicals - 1 Sept 2003
Court Michael H, Krishnaswamy Soundarajan, Hao Qin, Duan Su X, Patten Christopher J, Von Moltke Lisa L, Greenblatt David J
Abstract excerpt
UDP-glucuronosyltransferase 2B7 (UGT2B7) is involved in the glucuronidation of a wide array of clinically important drugs and endogenous compounds in humans. The aim of this study was to identify an isoform-selective probe substrate that could be used to investigate genetic and environmental infl...
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