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Article

Interaction protein for cytohesin exchange factors 1 (IPCEF1) binds cytohesin 2 and modifies its activity.

The Journal of biological chemistry - 31 Oct 2003

Venkateswarlu Kanamarlapudi

Abstract excerpt

The ADP-ribosylation factor 6 (ARF6) small GTPase functions as a GDP/GTP-regulated switch in the pathways that stimulate actin reorganization and membrane ruffling. The formation of active ARF6GTP is stimulated by guanine nucleotide exchange factors (GEFs) such as cytohesins, which translocate to the plasma membrane in agonist-stimulated cells by binding the lipid second messenger phosphatidylinositol...

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Source

Identifiers

PMID: 12920129
DOI: 10.1074/jbc.M304078200

Genes

IPCEF1
ARF6

Provenance

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Interaction protein for cytohesin exchange factors 1 (IPCEF1) binds cytohesin 2 and modifies its activity.PMID 12920129Read ↗

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