Article
Controlling small guanine-nucleotide-exchange factor function through cytoplasmic RNA intramers.
Proceedings of the National Academy of Sciences of the United States of America - 24 Apr 2001
Mayer G, Blind M, Nagel W, Böhm T, Knorr T, Jackson C L, Kolanus W, Famulok M
Abstract excerpt
ADP-ribosylation factor (ARF) GTPases and their regulatory proteins have been implicated in the control of diverse biological functions. Two main classes of positive regulatory elements for ARF have been discovered so far: the large Sec7/Gea and the small cytohesin/ARNO families, respectively. These proteins harbor guanine-nucleotide-exchange factor (GEF) activity exerted by the common Sec7 domain. The...
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