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Article

Cyclin D1 repression of peroxisome proliferator-activated receptor gamma expression and transactivation.

Molecular and cellular biology - 1 Sept 2003

Wang Chenguang, Pattabiraman Nagarajan, Zhou Jian Nian, Fu Maofu, Sakamaki Toshiyuki, Albanese Chris, Li Zhiping, Wu Kongming, Hulit James, Neumeister Peter, Novikoff Phyllis M, Brownlee Michael, Scherer Philipp E, Jones Joan G, Whitney Kathleen D, Donehower Lawrence A, Harris Emily L, Rohan Thomas, Johns David C, Pestell Richard G

Abstract excerpt

The cyclin D1 gene is overexpressed in human breast cancers and is required for oncogene-induced tumorigenesis. Peroxisome proliferator-activated receptor gamma (PPAR gamma) is a nuclear receptor selectively activated by ligands of the thiazolidinedione class. PPAR gamma induces hepatic steatosis...

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Source

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Identifiers

PMID: 12917338
DOI: 10.1128/MCB.23.17.6159-6173.2003
PMCID: PMC180960

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12917338-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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