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Article

Multiple functions of D-type cyclins can antagonize pRb-mediated suppression of proliferation.

Cell cycle (Georgetown, Tex.) - 1 Feb 2005

Baker Gregory L, Landis Mark W, Hinds Philip W

Abstract excerpt

The most well understood function of the D-type cyclins is to activate the G(1) kinases, cdk4 and cdk6, and target the retinoblastoma gene product (pRb) for phosphorylation and inactivation. pRb can suppress S phase entry, cause a transient G(1) arrest following DNA damage, and is critical in est...

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Identifiers

PMID: 15684604

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15684604-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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