Article
Enhancement of BRCA1 gene expression by the peroxisome proliferator-activated receptor gamma in the MCF-7 breast cancer cell line.
Oncogene - 21 Aug 2003
Pignatelli Miguel, Cocca Claudia, Santos Angel, Perez-Castillo Ana
Abstract excerpt
BRCA1 has been linked to the genetic susceptibility of a majority of familial breast and ovarian cancers. Several lines of evidence indicate that BRCA1 is a tumor suppressor and its expression is downregulated in sporadic breast and ovarian cancer cases. Therefore, the identification of genes inv...
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