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Article

Extracellular signal-regulated kinase 7, a regulator of hormone-dependent estrogen receptor destruction.

Molecular and cellular biology - 1 Sept 2003

Henrich Lorin M, Smith Jeffrey A, Kitt Danielle, Errington Timothy M, Nguyen Binh, Traish Abdulmaged M, Lannigan Deborah A

Abstract excerpt

Estrogen receptor alpha (ER alpha) degradation is regulated by ubiquitination, but the signaling pathways that modulate ER alpha turnover are unknown. We found that extracellular signal-regulated kinase 7 (ERK7) preferentially enhances the destruction of ER alpha but not the related androgen rece...

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Identifiers

PMID: 12917323
DOI: 10.1128/MCB.23.17.5979-5988.2003
PMCID: PMC180983

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-12917323-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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