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Article

Let-7: A regulator of the ERα signaling pathway in human breast tumors and breast cancer stem cells

6 Mar 2013

Abstract excerpt

The oncogenic role of estrogen receptor (ER)α and its correlation with let-7 microRNAs (miRNAs) have been studied and confirmed in breast tumors; however, this correlation has not been investigated in breast cancer stem cells (BCSCs). In the present study, we detected the expression of let-7 and ERα in ER-positive breast tumor tissues. Furthermore, we used a FACSAria cell sorter to separate side population (SP)...

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Identifiers

PMID: 23467929
DOI: 10.3892/or.2013.2330

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