Article
Protein phosphatase 5 is a negative regulator of estrogen receptor-mediated transcription.
Molecular endocrinology (Baltimore, Md.) - 1 May 2004
Ikeda Kazuhiro, Ogawa Sumito, Tsukui Tohru, Horie-Inoue Kuniko, Ouchi Yasuyoshi, Kato Shigeaki, Muramatsu Masami, Inoue Satoshi
Abstract excerpt
Estrogen receptors (ERs) are transcription factors that can be modulated by both estrogen-dependent and growth factor-dependent phosphorylation. A yeast two-hybrid screening identified a serine/threonine protein phosphatase (PP5) as an interactant of ERbeta (1-481), a dominant negative ERbeta mut...
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