Article
Relationship between gene polymorphisms of mannose-binding lectin (MBL) and two molecular forms of MBL.
European journal of immunology - 1 Oct 2003
Terai Itaru, Kobayashi Kunihiko, Matsushita Masanao, Miyakawa Hiroshi, Mafune Naoki, Kikuta Hideaki
Abstract excerpt
Mannose-binding lectin (MBL) activates complement through MBL-associated serine proteases (MASP). A deficiency in MBL due to mutations at exon 1 of the human MBL gene is reported to cause vulnerability to infection. We examined sera of known MBL genotype by gel filtration and assessed their eluti...
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