Article
Mannose binding lectin (MBL) genotype distributions with relation to serum levels in UK Caucasoids.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Jun 2000
Crosdale D J, Ollier W E, Thomson W, Dyer P A, Jensenious J, Johnson R W, Poulton K V
Abstract excerpt
Mannose binding lectin (MBL) gene and promoter-region polymorphisms contribute to a reduction in the levels of circulating MBL in a number of ways. Promoter polymorphisms affect the levels of MBL produced, whilst structurally encoding mutations cause non-functional protein to be assembled and subsequently degraded. MBL is important as a protein of the innate immune system in both the clearance of potential...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
