Article
LKB1 protein expression in the evolution of glandular neoplasia of the lung.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Aug 2003
Ghaffar Hassan, Sahin Fikret, Sanchez-Cepedes Montserrat, Su Gloria H, Zahurak Marianna, Sidransky David, Westra William H
Abstract excerpt
PURPOSE: About one-third of sporadic lung adenocarcinomas demonstrates biallelic inactivation of the LKB1 gene, but the timing of this event is not known. DESIGN: We performed LKB1 immunohistochemistry on 35 primary lung adenocarcinomas and 96 atypical adenomatous hyperplasias (AAH), a form of ea...
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