Article
Lack of association of the plasminogen activator inhibitor-1 4G/5G promoter polymorphism with cardiovascular disease in the elderly.
Journal of thrombosis and haemostasis : JTH - 1 Aug 2003
Crainich P, Jenny N S, Tang Z, Arnold A M, Kuller L H, Manolio T, Sharrett A R, Tracy R P
Abstract excerpt
Elevated circulating plasminogen activator inhibitor-1 (PAI-1) may increase risk of cardiovascular disease (CVD). The 4G allele of the 4G/5G PAI-1 promoter polymorphism is associated with higher levels of PAI-1. We examined the association of PAI-1 4G/5G genotype and CVD events in the elderly par...
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