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Article

The 4G/5G polymorphism in the plasminogen activator inhibitor-1 gene is not associated with myocardial infarction.

Thrombosis and haemostasis - 1 Jul 1999

Doggen C J, Bertina R M, Cats V M, Reitsma P H, Rosendaal F R

Abstract excerpt

Several studies have found an association between high plasminogen activator inhibitor-1 (PAI-1) levels and myocardial infarction. Whether this is causal or a consequence of atherosclerosis or tissue damage, remains unclear. Homozygous carriers of the 4G allele of the 4G/5G polymorphism in the PA...

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PMID: 10456464

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-10456464-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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The 4G/5G polymorphism in the plasminogen activator inhibitor-1 gene is not associated with myocardial infarction.PMID 10456464Read ↗

Plasminogen activator inhibitor-1 promoter 4G/5G genotype is not a risk factor for myocardial infarction in a Japanese population.Semantic proximity Read ↗

Lack of association of a common polymorphism of the plasminogen activator inhibitor-1 gene with coronary artery disease and myocardial infarction.Semantic proximity Read ↗

Arterial and venous thrombosis is not associated with the 4G/5G polymorphism in the promoter of the plasminogen activator inhibitor gene in a large cohort of US men.Semantic proximity Read ↗

Plasminogen activator inhibitor-1 4G/5G-polymorphism and factor V Q506 mutation are not associated with myocardial infarction in young men.Semantic proximity Read ↗

Reduced carriership of 4G allele of plasminogen activator inhibitor-1 4G/5G polymorphism in very young survivors of myocardial infarction.Semantic proximity Read ↗

Plasminogen activator inhibitor type 1 gene polymorphisms and haplotypes are associated with plasma plasminogen activator inhibitor type 1 levels but not with myocardial infarction or stroke.Semantic proximity Read ↗

Plasminogen Activator Inhibitor-1 Promoter 4G/5G Genotype and Plasma Levels in Relation to a History of Myocardial Infarction in Patients Characterized by Coronary AngiographySemantic proximity Read ↗

Lack of association of the plasminogen activator inhibitor-1 4G/5G promoter polymorphism with cardiovascular disease in the elderly.Semantic proximity Read ↗

The association of PAI-1 promoter 4G/5G insertion/deletion polymorphism with myocardial infarction and stroke in young women.Semantic proximity Read ↗

Genetic variation in coagulation and fibrinolytic proteins and their relation with acute myocardial infarction: a systematic review.Semantic proximity Read ↗

4G/5G polymorphism and haplotypes of SERPINE1 in atherosclerotic diseases of coronary arteries.Semantic proximity Read ↗

Plasminogen activator inhibitor-1 (PAI-1) 4G/5G polymorphism, coronary thrombosis, and myocardial infarction in middle-aged Finnish men who died suddenly.Semantic proximity Read ↗

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