Article
Kinetics of conformational transitions in cardiac troponin induced by Ca2+ dissociation determined by Förster resonance energy transfer.
The Journal of biological chemistry - 24 Oct 2003
Dong Wen-Ji, Robinson John M, Xing Jun, Cheung Herbert C
Abstract excerpt
Upon Ca2+ activation of cardiac muscle, several structural changes occur in the troponin subunits. These changes include the opening of the cardiac troponin C (cTnC) N-domain, the change of secondary structure of the inhibitory region of cardiac troponin I (cTnI), and the change in the separation...
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