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Article

Overexpression of cyclin A overrides the effect of p53 alterations in breast cancer patients with long follow-up time.

Breast cancer research and treatment - 1 Jul 2003

Bukholm Ida R K, Husdal Anne, Nesland Jahn M, Langerød Anita, Bukholm Geir

Abstract excerpt

The tumour suppressor gene p53 and its protein controls critical cellular functions in cell cycle regulation as well as in apoptosis. Recently, in an in vitro study on breast cancer cell line MCF-7, the apoptotic function of p53 has been shown to be altered by overexpression of cyclin A. In this...

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Identifiers

PMID: 12908823
DOI: 10.1023/A:1024527220362

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-12908823-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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