Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The prognostic value and overexpression of cyclin A is correlated with gene amplification of both cyclin A and cyclin E in breast cancer patient.

Cellular oncology : the official journal of the International Society for Cellular Oncology - 1 Jan 2006

Husdal A, Bukholm G, Bukholm I R K

Abstract excerpt

UNLABELLED: Deregulation of cell cycle control is a hallmark of cancer. The primary cyclins (A, B1, D1, D3 and E) are crucial for cell cycle progression. Secondary cyclins (C and H) have putative indirect effects on cell cycle propulsion and are not previously evaluated in breast cancer. We have examined protein expression and gene amplification of cyclins in breast carcinomas and correlated the findings with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cyclin A
Share to Cyclin E

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Gene Amplification

Share to Gene Expression Regulation, Neoplastic

Share to Genes, p53

Share to Multivariate Analysis

Share to Neoplasm Staging

Source

Open in PubMed Open full text

Identifiers

PMID: 16823179
DOI: 10.1155/2006/721919
PMCID: PMC4615173

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The prognostic value and overexpression of cyclin A is correlated with gene amplification of both cyclin A and cyclin E in breast cancer patient.PMID 16823179Read ↗

A comprehensive analysis of Aurora A; transcript levels are the most reliable in association with proliferation and prognosis in breast cancerSemantic proximity Read ↗

E- and A-type cyclins as markers for cancer diagnosis and prognosisSemantic proximity Read ↗

Overexpression of cyclin A overrides the effect of p53 alterations in breast cancer patients with long follow-up time.Semantic proximity Read ↗

Expression and gene amplification of primary (A, B1, D1, D3, and E) and secondary (C and H) cyclins in colon adenocarcinomas and correlation with patient outcomeSemantic proximity Read ↗

Gene Amplification and Overexpression of Aurora-C in Breast and Prostate Cancer Cell LinesSemantic proximity Read ↗

Cyclin gene amplification and overexpression in breast and ovarian cancers: Evidence for the selection ofcyclin D1 in breast andcyclin E in ovarian tumorsSemantic proximity Read ↗

Redundant cyclin overexpression and gene amplification in breast cancer cells.Semantic proximity Read ↗

Expression and amplification of Her2, EGFR and cyclin D1 in breast cancer: Immunohistochemistry and chromogenic in situ hybridizationSemantic proximity Read ↗

Cyclin D1 protein overexpression and CCND1 amplification in breast carcinomas: an immunohistochemical and chromogenic in situ hybridisation analysisSemantic proximity Read ↗

Prognostic Relevance of Gene Amplifications and Coamplifications in Breast CancerSemantic proximity Read ↗

Amplification of the MDM2 gene in human breast cancer and its association with MDM2 and p53 protein statusSemantic proximity Read ↗

Amplified centrosomes in breast cancer: a potential indicator of tumor aggressiveness.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.