Article
Genetic polymorphisms of platelet adhesive molecules: association with breast cancer risk and clinical presentation.
Breast cancer research and treatment - 1 Jul 2003
Ayala Francisco, Corral Javier, González-Conejero Rocío, Sánchez Ignacio, Moraleda José María, Vicente Vicente
Abstract excerpt
The main platelet adhesive receptors integrin alpha2beta1, integrin alphaIIbbeta3 and glycoprotein (GP) Ibalpha are also expressed in breast carcinoma cells. They play a key role in tumor cell-induced platelet aggregation and in adhesive interactions necessary for tumoral invasion and metastasis....
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