Article
The platelet glycoprotein Ibalpha VNTR polymorphism is associated with risk for oral cancer.
Anticancer research - 1 Jan 2000
Vairaktaris Eleftherios, Serefoglou Zoe Charalambous, Yapijakis Christos, Vassiliou Stavros, Nkenke Emeka, Avgoustidis Dimitris, Vylliotis Antonis, Stathopoulos Panagiotis, Neukam Friedrich W, Patsouris Efstratios
Abstract excerpt
BACKGROUND: We have previously found an association of platelet glycoprotein Ia polymorphism with increased risk for oral cancer. The purpose of this study was to investigate the possible relation of another platelet glycoprotein, Iba (GPIbalpha), with oral oncogenesis. PATIENTS AND METHODS: The variable number of tandem repeats (VNTR) polymorphism of the GPIbalpha gene, which affects the protein's structure and...
Topics
- Adult
- Aged
- Aged, 80 and over
- Alleles
- Blood Platelets
- Carcinoma, Squamous Cell
- Female
- Genetic Predisposition to Disease
- Genotype
- Humans
- Male
- Middle Aged
- Minisatellite Repeats
