Article
Apolipoprotein A1 -75 G/A and +83 C/T polymorphisms: susceptibility and prognostic implications in breast cancer.
Molecular biology reports - 1 Mar 2011
Hamrita Bechr, Ben Nasr Hela, Gabbouj Sallouha, Bouaouina Noureddine, Chouchane Lotfi, Chahed Karim
Abstract excerpt
Apolipoprotein A1 (ApoA1) is the major apoprotein constituent of high-density lipoprotein that can play important roles in tumor invasion and metastasis. In the current report, we evaluated the role of the functional ApoA1 polymorphisms (-75 G/A and +83 C/T) as genetic markers for breast cancer susceptibility and prognosis. We used the polymerase chain reaction and restriction enzyme digestion (RFLP-PCR) to...
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