Article
Response of heat shock element within the human HSP70 promoter to mutated p53 genes.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 1 Jan 1995
Tsutsumi-Ishii Y, Tadokoro K, Hanaoka F, Tsuchida N
Abstract excerpt
Recent studies have demonstrated that mutation of the p53 gene caused a gain of new functions such as transforming activation, binding to heat shock cognate protein 70 and/or transactivation of a variety of promoters. In the course of seeking the biochemical basis for the gain of these functions, we have noticed the correlation between transforming activity of different mutated p53 genes and their...
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