Article
Inference in linkage analysis of multifactorial traits using recombinant inbred strains of mice.
Behavior genetics - 1 Nov 1992
Neumann P E
Abstract excerpt
Recombinant inbred strains have been shown to be important tools for segregation and linkage analysis of multifactorial traits. Tests of association have been used as robust methods of linkage detection, however, guidelines for forming inferences from significance levels have not been generally available. In this paper, lessons learned from a Bayesian statistical approach to linkage analysis of Mendelian traits...
Topics
- Animals
- Crosses, Genetic
- Genetic Linkage
- Genetic Variation
- Mice
- Mice, Inbred Strains
- Models, Genetic
- Phenotype
- Recombination, Genetic
