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Article

Quantitative trait locus analysis using recombinant inbred intercrosses: theoretical and empirical considerations.

Genetics - 1 Jul 2005

Zou Fei, Gelfond Jonathan A L, Airey David C, Lu Lu, Manly Kenneth F, Williams Robert W, Threadgill David W

Abstract excerpt

We describe a new approach, called recombinant inbred intercross (RIX) mapping, that extends the power of recombinant inbred (RI) lines to provide sensitive detection of quantitative trait loci (QTL) responsible for complex genetic and nongenetic interactions. RIXs are generated by producing F1 hybrids between all or a subset of parental RI lines. By dramatically extending the number of unique, reproducible...

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Identifiers

PMID: 15879512
DOI: 10.1534/genetics.104.035709
PMCID: PMC1451174

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