Article
Type I and type II error rates for quantitative trait loci (QTL) mapping studies using recombinant inbred mouse strains.
Behavior genetics - 1 Mar 1996
Belknap J K, Mitchell S R, O'Toole L A, Helms M L, Crabbe J C
Abstract excerpt
Effective mapping strategies for quantitative trains must allow for the detection of the more important quantitative trait loci (QTLs) while minimizing false positives. Type I (false-positive) and Type II (false-negative) error rates were estimated from a computer simulation of QTL mapping in the BXD recombinant inbred (RI) set compromising 26 strains of mice, and comparisons made with theoretical predictions....
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