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Article

KIR2DL4 (CD158d) genotype influences expression and function in NK cells.

Journal of immunology (Baltimore, Md. : 1950) - 15 Aug 2003

Goodridge Jodie P, Witt Campbell S, Christiansen Frank T, Warren Hilary S

Abstract excerpt

The expression and function of the NK cell receptor KIR2DL4 are controversial. Two common alleles of the transmembrane domain of KIR2DL4 exist. The 10A allele with 10 adenines at the end of the transmembrane exon encodes a full length receptor, whereas the 9A allele has only 9 adenines resulting in a frame shift which in turn generates a stop codon early in the first cytoplasmic exon. The possibility that the 10A...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12902476
DOI: 10.4049/jimmunol.171.4.1768

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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