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Article

Identification of glucocorticoid receptor domains involved in transrepression of transforming growth factor-beta action.

The Journal of biological chemistry - 24 Oct 2003

Li Gangyong, Wang Shengfu, Gelehrter Thomas D

Abstract excerpt

The transforming growth factor-beta (TGF-beta) and glucocorticoid signaling pathways interact both positively and negatively in regulating a variety of physiological and pathologic processes. We previously reported that liganded glucocorticoid receptor (GR) repressed TGF-beta induction of human plasminogen activator inhibitor-1 gene transcription by directly targeting the transcriptional activation function of...

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PMID: 12902338
DOI: 10.1074/jbc.M305350200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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