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Article

Genetic susceptibility to enteroaggregative Escherichia coli diarrhea: polymorphism in the interleukin-8 promotor region.

The Journal of infectious diseases - 15 Aug 2003

Jiang Zhi-Dong, Okhuysen Pablo C, Guo Dong-Chuan, He Rumin, King Terri M, DuPont Herbert L, Milewicz Dianna M

Abstract excerpt

Enteroaggregative Escherichia coli (EAEC) infection can be identified in 26% of travelers with diarrhea and is associated with fecal interleukin (IL)-8 production. We hypothesized that single-nucleotide polymorphisms (SNPs) in the IL-8 gene are associated with EAEC-related symptoms. Fecal IL-8 production and IL-8 SNPs at 5 loci were identified in 69 US students who remained in Mexico for 5 weeks; 23 subjects had...

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Identifiers

PMID: 12898436
DOI: 10.1086/377102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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