Article
Association of interleukin-8 polymorphism and immunoglobulin G anti-toxin A in patients with Clostridium difficile-associated diarrhea.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association - 1 Aug 2007
Jiang Zhi-Dong, Garey Kevin W, Price Margaret, Graham Gail, Okhuysen Pablo, Dao-Tran Thanh, LaRocco Mark, DuPont Herbert L
Abstract excerpt
BACKGROUND & AIMS: Previous studies have shown that failure to produce serum antibodies to C. difficile (CD) toxin A is associated with more severe and recurrent C. difficile-associated diarrhea (CDAD); and that presence of AA genotype in the interleukin (IL)-8 gene promoter -251 position is associated with increased susceptibility to CDAD. This study examined the relationship between serum immunoglobulin G...
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