Article
Influence of host interleukin-10 polymorphisms on development of traveler's diarrhea due to heat-labile enterotoxin-producing Escherichia coli in travelers from the United States who are visiting Mexico.
Clinical and vaccine immunology : CVI - 1 Aug 2008
Flores Jose, DuPont Herbert L, Lee Stephanie A, Belkind-Gerson Jaime, Paredes Mercedes, Mohamed Jamal A, Armitige Lisa Y, Guo Dong-Chuan, Okhuysen Pablo C
Abstract excerpt
Up to 60% of U.S. visitors to Mexico develop traveler's diarrhea (TD), mostly due to enterotoxigenic Escherichia coli (ETEC) strains that produce heat-labile (LT) and/or heat-stable (ST) enterotoxins. Distinct single-nucleotide polymorphisms (SNPs) within the interleukin-10 (IL-10) promoter have been associated with high, intermediate, or low production of IL-10. We conducted a prospective study to investigate...
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