Article
Replication checkpoint kinase Cds1 regulates recombinational repair protein Rad60.
Molecular and cellular biology - 1 Aug 2003
Boddy Michael N, Shanahan Paul, McDonald W Hayes, Lopez-Girona Antonia, Noguchi Eishi, Yates III John R, Russell Paul
Abstract excerpt
Genome integrity is protected by Cds1 (Chk2), a checkpoint kinase that stabilizes arrested replication forks. How Cds1 accomplishes this task is unknown. We report that Cds1 interacts with Rad60, a protein required for recombinational repair in fission yeast. Cds1 activation triggers Rad60 phosph...
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