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Article

Association between polymorphisms in the human chemokine receptor genes CCR2 and CX3CR1 and rheumatoid arthritis.

Tissue antigens - 1 Aug 2003

Bayley J-P, Baggen J M, van der Pouw-Kraan T, Crusius J B A, Huizinga T W J, Verweij C L

Abstract excerpt

Cell trafficking into the rheumatoid synovium is thought to play an important role in the inflammation seen in rheumatoid arthritis. Chemokine receptors play a central role in this process, and several common variants are known, including the CCR2 variant, CCR2-64I, and two variants of the CX3CR1 gene, V249I and T280M. All three variants result in functional amino acid substitutions. We studied the association of...

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Share to Arthritis, Rheumatoid
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Variation

Share to Membrane Proteins

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Share to Polymorphism, Genetic

Share to Receptors, CCR2

Share to Receptors, Chemokine

Source

Identifiers

PMID: 12889997
DOI: 10.1034/j.1399-0039.2003.00073.x

Genes

CCR2

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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