Article
CCR5 gene polymorphism is a genetic risk factor for radiographic severity of rheumatoid arthritis.
Tissue antigens - 1 Nov 2012
Han S W, Sa K H, Kim S I, Lee S I, Park Y W, Lee S S, Yoo W H, Soe J S, Nam E J, Lee J, Park J Y, Kang Y M
Abstract excerpt
The chemokine receptor [C-C chemokine receptor 5 (CCR5)] is expressed on diverse immune effecter cells and has been implicated in the pathogenesis of rheumatoid arthritis (RA). This study sought to determine whether single-nucleotide polymorphisms (SNPs) in the CCR5 gene and their haplotypes were associated with susceptibility to and severity of RA. Three hundred fifty-seven patients with RA and 383 healthy...
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