Article
The chemokine CX3CL1 (fractalkine) and its receptor CX3CR1: occurrence and potential role in osteoarthritis.
Archivum immunologiae et therapiae experimentalis - 1 Oct 2014
Wojdasiewicz Piotr, Poniatowski Lukasz A, Kotela Andrzej, Deszczyński Jarosław, Kotela Ireneusz, Szukiewicz Dariusz
Abstract excerpt
Chemokines are molecules able to induce chemotaxis of monocytes, neutrophils, eosinophils, lymphocytes and fibroblasts. The complex chemokine acts in many physiological and pathological phenomena, including those occurring in the articular cartilage. To date, chemokine CX3CL1 (fractalkine) is the only member of the CX3C class of chemokines with well-documented roles in endothelial cells. CX3CL1 is a unique...
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