Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation at the CCR5/CCR2 gene cluster and risk of psoriasis and psoriatic arthritis.

Cytokine - 1 May 2010

Soto-Sánchez Javier, Santos-Juanes Jorge, Coto-Segura Pablo, Coto Eliecer, Díaz Marta, Rodríguez Isabel, Alvarez Victoria

Abstract excerpt

OBJECTIVES: Inflammation plays a major role in psoriasis (Ps). The variation at several genes that encode components of the inflammatory pathways have been linked to the risk for Ps. Our objective was to examine the association between Ps and three polymorphisms at the chemokine receptors CCR5 and CCR2. METHODS: A total of 382 Ps patients and 500 healthy controls from Spain were genotyped for the CCR5-32bp...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Arthritis, Psoriatic
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genetic Predisposition to Disease

Share to Multigene Family

Share to Polymorphism, Genetic

Share to Receptors, CCR2

Share to Receptors, CCR5

Source

Identifiers

PMID: 20153665
DOI: 10.1016/j.cyto.2010.01.006

Genes

CCR2
CCR5

Variants

rs1799988

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation at the CCR5/CCR2 gene cluster and risk of psoriasis and psoriatic arthritis.PMID 20153665Read ↗

The association of genetic variants in chemokine genes with the risk of psoriasis vulgaris in Chinese population: A case-control study.Semantic proximity Read ↗

Analysis of chromosome 5q31-32 and psoriasis: confirmation of a susceptibility locus but no association with SNPs within SLC22A4 and SLC22A5.Semantic proximity Read ↗

Analysis of genetic variants of class II cytokine and their receptor genes in psoriasis patients of two ethnic groups from the Volga-Ural region of Russia.Semantic proximity Read ↗

CCR5 gene polymorphism is a genetic risk factor for radiographic severity of rheumatoid arthritis.Semantic proximity Read ↗

Genetic polymorphisms associated with psoriasis and development of psoriatic arthritis in patients with psoriasis.Semantic proximity Read ↗

Association between single nucleotide polymorphisms IL17RA rs4819554 and IL17E rs79877597 and Psoriasis in a Spanish cohort.Semantic proximity Read ↗

Chemokine receptor CCR2/CCR5 polymorphism in Spanish patients with systemic lupus erythematosus.Semantic proximity Read ↗

TLR2 and TLR4 polymorphisms in Southern Chinese Psoriasis Vulgaris patients.Semantic proximity Read ↗

PSORS2 markers are not associated with psoriatic arthritis in the Italian population.Semantic proximity Read ↗

Genotypes of CCR2 and CCR5 chemokine receptors in human myasthenia gravis.Semantic proximity Read ↗

CCR5 promoter region polymorphisms in systemic lupus erythematosus.Semantic proximity Read ↗

Investigation of the genetic overlap between rheumatoid arthritis and psoriatic arthritis in a Greek population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.