Article
Molecular characterization of oncostatin M-induced growth arrest of MCF-7 cells expressing a temperature-sensitive mutant of p53.
Breast cancer research and treatment - 1 Jul 2003
Li Cong, Shridhar Kunju, Liu Jingwen
Abstract excerpt
Our previous studies have shown that treatment of MCF-7 breast cancer cells with cytokine oncostatin M (OM) results in a growth arrest and a concurrent decrease in p53 expression. It remains to be determined whether these two important events are directly connected, as changes in p53 protein leve...
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